A Persistent Hypertension due to Unilateral Renal-Artery Constriction in the Rabbit

JUN FUJII; HIROSHI KURIHARA; HIROSHI YAMAGUCHI; FUJIO TERASAWA; KAZUHIKO MURATA; SATORU MATSUSHITA; MASAO IKEDA

doi:10.1253/jcj.31.1197

JUN FUJII, HIROSHI KURIHARA, HIROSHI YAMAGUCHI, FUJIO TERASAWA, KAZUHIKO MURATA, SATORU MATSUSHITA, MASAO IKEDA

著者情報

ジャーナルフリー

1967 年 31 巻 8 号 p. 1197-1200

DOI https://doi.org/10.1253/jcj.31.1197

詳細

抄録

Unilateral renal-artery constriction was performed in salt-fed (0.5g/day) rabbits with a silver clip (diameter: 0.9 mm), contralateral kidney being left intact. At the end of 10 weeks after the unilateral renal-artery constriction a persistent rise of blood pressure to over the upper normal limit of 120mmHg was observed in 10 of 22 treated rabbits. The blood pressure remained raised for over 6 months in 8 rabbits. In spite of the persistent hypertension no rabbits died on hypertensive vascular diseases.

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