Abstract
Ajimaline increased the total sodium content of rat hearts including the atria and ventricles. Diphenylhydantoin and propranolol decreased the potassium content of the intracellular compartments. Propranolol caused a decrease of the potassium content of rat ventricles. The decrease of potassium became significantly milder by the addition of digitalis to propranolol. There were no changes in the sodium and potassium concentrations of rat sera treated with the drugs in these experiments.
