抄録
A quantative description for histological observation of myocardial lesion was proposed. Left venticle was divided into 25 divisions. Whole paraffin sections were made from each of them, and stained by haematoxylin-eosin and Azan method. The extent and kind of myocardial lesions of these samples were examined histologically. The results of the examination were described by "myocardial lesion profile" (M.P.) which was theoretically similar to Gore's atherosclerotic profile, M.P. was changed to "myocardial lesion index" (M.I.) by a simple calculation. It is possible to express the grade of pathologic changes of myocardium as a number of myocardial lesion index. The grades of the myocardial lesions could be compared quantitatively with those of other samples. The mean values of index in many cases can be also obtained. It was shown that the myocardial lesions of hypertensive hearts were much severer than those of non-hypertensive ones. The lesions of the former were severest at the upper ventricular septum near the aortic ostium ; it might be the hemodynamic influences of blood pressure which becomes highest at the aortic ostium (Fig.14).
