Abstract
No significant elevation of blood pressure was observed in control Wistar rats parabiotically united with spontaneously hypertensive rats (SHR). SHR showed a slight lowering of blood pressure when they were united with control Wistar rats, but such a lowering effect was not obvious in SHR united w:th unilaterally nephrectomized Wistar rats. The blood pressure of the partner of SHR parabiotics maintained hypertension for 10 days after bilateral nephrectomy. These results showed that SHR had no humoral transmissible pressor substance and that the kidney of SHR had no positive role in maintaining hypertension.
