Abstract
A qualitative analysis of serum lipoproteins in 123 cerebrovascular patients and 138 controls was carried out by a modified polyacrylamide gel disc electrophoresis in order to investigate the contribution of lipoproteins to cerebrovascular disorders. Mid-band lipoproteins were present in 148 of 261 over-all subject .Furthermore, in these subjects with mid-band lipoproteins, higher levels of serum total cholesterol and triglyceride were found when compared to the subjects without mid-band lipoproteins. Mid-band lipoproteins were detected significantly more frequently in patients than in controls .The incidence of mid-band lipoproteins among the patients with cerebral infarction was higher than that among those with hemorrhage, and was higher in the patients with abnormal electrocardiographic findings or impaired renal functions compared to those without them. The incidence of mid-band lipoproteins in patients was not affected by hyperlipidemia. However, in controls, the incidence was higher in hyperlipidemics than in normolipidemics. In normolipidemic subjects, the incidence of mid-band lipoproteins was higher in cerebrovascular patients than in controls, suggesting existence of abnormal lipoprotein metabolsim even in normolipidemic cerebrovascular patients.
