抄録
Cardiac functions of 28 patients long after correction of tetralogy of Fallot (TOF) were examined using non-invasive and invasive methods. For comparison the patients were grouped in 2 different ways: those with a right ventricular systolic pressure below 50 mmHg (Group A, n = 10) and above 50 mmHg (Group B, n = 18) in the early post-operative stage ; those having an ability to complete the treadmill test (Group I, n = 14) and those without it (Group II, n = 10). The following results were obtained by our study performed more than 10 years after surgery : 1) Group A showed no differences in all parameters studied as compared with Group B. 2) As compared with the normal subjects ( control group, n = 20), the patients had a larger cardio-thoracic ratio (CTR) and a larger right/left ventricular dimension ratio (RVD/LVD), but showed no differences in percent fractional shortening (%FS), mean velocity of circumferential fiber shortening (mVcf), corrected ejection time (ETc) and ejection fraction(EF). 3) As compared with Group I, Group II had a larger CTR, a larger RVD/LVD ratio, and continued higher levels of the right/left ventricular systolic pressure ratio (RVP/LVP) and right ventricular pulmonary systolic pressure gradient (PG), but showed no differences in %FS, mVcf, ETc, EF and pulmonary artery pulse pressure/pulmonary arterial systolic pressure ratio. 4) Eight patients, all belonging to Group II, , had ventricular arrhythmia (Lown's grade 3 or 4). 5) Severe pulmonary regurgitation (PR) was noted in Group II. At a later time long after the correction of TOF, RVP, PG, PR and arrhythmia are considered to be important parameters for evaluating the cardiac status in this disorder.
