Oxygen Therapy and Vasodilator Therapy in Patients with Chronic Lung Disease : The Effects on Episodic Pulmonary Hypertension During Sleep and Exercise Performance : SYMPOSIUM ON COR PULMONALE

Abstract

In patients with chronic lung disease, we estimated the effectiveness of nocturnal oxygen therapy in eliminating episodes of sleep hypoxemia and concomitant elevations in the pulmonary arterial pressure. We also assessed the effect of vasodilators (ISDN, nifedipine) in improving exercise tolerance. Our results support the efficacy of nocturnal oxygen therapy. Visodilators examined were not confirmed as effective or safe for wide use.