1991 Volume 55 Issue 2 Pages 117-124
This clinical study was undertaken to evaluate resting left ventricular early diastolic function relating to perioperative myocardial damage after coronary artery bypass graft (CABG) with radionuclide ventriculography. Forty-eight cases undergoing CABG were divided into two groups-Group I: not complicated with perioperative myocardial infarction (PMI), and Group II: complicated with PMI. In Group I (42 cases), early diastolic parameters such as peak filling rate (1/3 PFR) and mean filling rate (1/3 FR(m)) during first third diastole were not impaired in the postoperative and follow up periods. In contrast, in Group 11 (6 cases), early diastolic parameters were significantly de-creased to 157±74% EDV/sec of 1/3 PFR(pre op: 234±74, p<0.05) and 153±80% EVD/sec of 1/3 FR(m) (pre op: 231±86, p<0.05) in the postoperative period, and these parameters were still decreased in follow up period. The time to peak filling rate, normalized to diastolic time (TPFR/DT) of Group II cases, was severely prolonged in both periods. From these results, the complication of perioperative myocardial infarction was suggested by the decrease of early diastolic function and the prolongation of the time to peak filling rate. Early diastolic function was a more sensitive parameter than systolic function in the detection of impaired cardiac function in those cases with perioperative myocardial damage after CABG.
