Pharmaceutical Bulletin
Online ISSN : 1881-1345
Print ISSN : 0369-9471
ISSN-L : 0369-9471
Studies on Tetralin Derivatives. II. Ultraviolet Spectra of Hydroxytetralins and Hydroxytetralones
Tsutomu MomoseYosuke OhkuraShujiro Goya
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1955 Volume 3 Issue 6 Pages 401-406

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Abstract
The ultraviolet absorption spectra of hydroxytetralins, hydroxytetralones, their acetates, and their methyl ethers are compared. The spectra of hydroxytetralin derivatives consist of two bands, and that of hydroxytetralone derivatives, three bands. The introduction of a hydroxyl group to the aromatic ring of tetralin displaces the absorption band to a longer wave length region, increasing the intensity. The introduction of two hydroxyl groups, especially in 1, 4-positions, is more effective. The acetylation and the methylation of the hydroxyl group decrease the spectral effect of hydroxyl group in varying rates. Syntheses of some tetralin and tetralone derivatives are also described.
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© The Pharmaceutical Society of Japan
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