Sulfur-containing Pyridine Derivatives. XLVIII. Synthesis of Thiazolo[5, 4-c]pyridines

Abstract

The Synthesis of thiazolo[5, 4-c]pyridines was accomplished by the Curtius degradation of 3-mercaptoisonicotinic acid hydrazide and cyclization of the resulting 4-aminopyridine-3-thiol with formic acid or acetic anhydride.