Abstract
In the reaction of 3, 6-dichloro-4-methylpyridazine (I) with hydrazine hydrate, ammonia, sodium hydroxide, sodium methoxide, or potassium hydrogen sulfide, monosubstituted compounds were obtained. The position of methyl group in those compounds and the relationship among them were cleared up. Examination was also made on whether substitution in (I) occurred in 3- or in 6-position according to the change of conditions. 6-Chloro-8-methyl-s-triazolo [4, 3-b] pyridazine and 6-chloro-7-methyl-s-triazolo [4, 3-b]-pyridazine were prepared from 3-hydrazino-4-methyl-6-chloropyridazine and 3-hydrazino-5-methyl-6-chloropyridazine, and were derived to their 6-hydrazino derivatives.
