抄録
We describe an unusual presentation of virilizing adrenal adenoma in a prepubertal girl. The patient's adrenal mass had been detected incidentally at one year of age, but no clinical signs were evident until the appearance of pubic hair at 7 years of age. Plasma testosterone concentration was elevated (166ng/dl), but further endocrinological examination revealed prominent elevation of δ5-pregnene steroids including 17-hydroxypregnenolone, dehydroepiandrosterone and dehydroepiandrosterone-sulfate. Finally, a diagnosis of adrenocortical adenoma was made after surgical resection. This adrenal tumor, clinically non-functional early, was considered to be “late functioning”.
