Abstract
Deep vein thrombosis (DVT) is a serious complication after lower extremity surgery. We investigated the effectiveness and safety of anticoagulation therapy with medicine during post surgical period.
The number of samples was 54. We divided patients into two groups; 25 patients with anticoagulation therapy and 29 without it. Before operation, we examined lower extremities with ultrasonography to confirm that they don’t have DVT. The former group was given Heparin for two days and Warfarin for one month as anticoagulation therapy. After 1 week, we also examined the lower extremities by ultrasonography. We checked the degree of bleeding, the reduction of hemoglobin, and the incidence of DVT.
The mean amount of post-operative bleeding was 420 ml in the former group and 457 ml in the latter group (p＞0.05). The reduction of hemoglobin indicated 1.42 g/dl and 1.29 g/dl respectively (p＞0.05). DVT was found in three out of 25 in the former group and four out of 29 in latter group (p＞0.05).
It could be concluded that it was safe though it had no tangible evidence for its effectiveness. Hence, further examination would be needed with higher dose of anticoagulation.
