2016 Volume 28 Issue 2 Pages 150-157
Anti-synthetase syndrome (ASS) is often accompanied by myositis, exanthema, and non-erosive arthritis. Especially, myositis with anti-PL-12 antibody often accompanied fever, Raynaud’s phenomenon, non-erosive arthritis and interstitial pneumonia. We present a 53-year-old male polyarthritis patient with fever, seborrheic area erythema and slight Gottron’s signs, without interstitial pneumonia. CK level was within the normal range, but aldolase level was elevated. DWIBS (diffusion weighted whole body imaging with background body signal suppression) showed several high regions. In addition, anti-PL-12 antibody was positive. We diagnosed him with dermatomyositis and treated him with prednisolone 50 mg/day (1mg/kg/day). On day 59 of the hospitalization, he was discharged to return home and has had favorable course since then. DWIBS provides noninvasively useful information for diagnosing myositis. This case suggests the applicability of DWIBS in the diagnosis of systemic disease.
