The concept of drug therapy and challenges in T2T

Abstract

  The concept of treat to target（T2T）, in which the risks of the disease are comprehensively evaluated and taken to a very low level within an acceptable period, is becoming waidespread in the treatment of rheumatoid arthritis, subsequently in the treatment of spondyloarthritis and systemic lupus erythematosus. However, any uniform measurement of disease activity may not be suitable for a variety of patients with the same disease, and thus a gap is observed in the popularization between the concept and clinical practice of T2T. Emerging challenges include clinical evaluation of the patients in a super-aged society and the measurement of the blood trough level of biological agents. Therefore, the need for a multidisciplinary patient care is increasing more than ever.