A case of Rheumatoid arthritis with pulmonary non-tuberculosis mycobacterium who treated with methotrexate and Sarilumab
2020 Volume 32 Issue 3 Pages 186-193
Details
2020 Volume 32 Issue 3 Pages 186-193
A 79-year-old women was referred to our hospital because of severe arthritis. She had been having joint pain for more than 1 year and anti-CCP antibody was positive. She was diagnosed as having rheumatoid arthritis and treated with methotrexate and prednisolone. In addition, she was diagnosed as having non-tuberculosis mycobacterium according to sputum test for non-tuberculosis mycobacterium（NTM）and treated with chemotherapy for her NTM.
Her RA activity was very high and Sarilumab was added to her treatment in combination with methotrexate. After adding Sarilumab, her RA activity decreased. On the other hand, her PCR test for NTM was negative.
After 1 year, her RA was in remission. Sarilumab was decreased from 200 to 150 mg. Her RA has been in remission and NTM was also stable.
Our case suggests that it is possible that we may use biologics for patients with high disease activity RA who have pulmonary NTM if NTM remains stable.
