Abstract
The dry mixtures of calf thymus DNA (CT-DNA) with trehalose, neotrehalose, maltose and sucrose have been prepared by air-drying their aqueous solution. The dry CT-DNA, which normally exists in coiled or single-stranded structure, has been found to persist in double-stranded structure when imbedded in the four disaccharides. The double-stranding of dry CT-DNA should be resulted from the 'disaccharidation' effect of disaccharides, i.e. the interaction of disaccharides with the phosphate groups and possibly other polar groups of CT-DNA.
