Abstract
Examination using limulus amebocyte lysate test (LAL test) revealed a high concentration of endotoxin detected in the blood of patients under artificial heart lung, explaining some of postoperative pyrexia and heart lung dysfunction. However, the recently-developed endotoxin specific reaction test indicated only low concentration of endotoxin but high in limulus amebocyte lysate-reactive material in patients under artificial heart lung. We studied on the origin of the LAL-reactive material. Albumin preparations in use for artificial heart lung filler contains a high concentration of the above material, and the gauze ordinary used inside the pericardium elutes a high concentration of the above material in the blood.