Cell Structure and Function
Online ISSN : 1347-3700
Print ISSN : 0386-7196
ISSN-L : 0386-7196
Low-Amplified N-myc Gene and pp60src in Retinoblastoma TOTL-1 Cells which Undergo Neuron-Like Differentiation
Kazuhiko WabayashiSaoko AtsumiTetsuo SasabeShigeo Nori
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ジャーナル フリー

1989 年 14 巻 3 号 p. 331-343

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抄録
A cell line of retinoblastoma cells, TOTL-1, was established which hada very weakly amplified N-myc gene. It grew only in clumps that were hardly ever dispersed and showed retarded proliferation. Its doubling time was 160 h. TOTL-1 cells extended short thick processes in monolayer cultures on poly-D-lysine coated substratum, which were markedly different from those of Y79 cells. Light and electron microscopy observation of immunostaining with anti-pp60srcsrc antibody revealed that the staining was accumulated in the polar regions of the cells.
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© Japan Society for Cell Biology
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