Abstract
The protective effect of vitamin E was examined on inhibition by bisulfite of aggregations of dissociated embryonic quail liver cells in rotation-mediated cell culture. Bisulfite had a concentration-dependent inhibitory effect on the aggregation of cells. In the presence of 10-2M bisulfite, the mean diameters of aggregates formed after 24 and 48 h were less than half of those of aggregates in control cultures. Addition of 10-7M vitamin E significantly reduced the inhibitory effect of bisulfite on cell aggregation. A concentration of 10-5M vitamin E had the most protective effect on aggregation of embryonic liver cells.
