Kinetic Study of Immobilization due to Antigen-antibody Reaction in Paramecium caudatum, Stock K_A 6

Abstract

1. Kinetic theories of immobilization due to antigen-antibody reaction were developed, and experimental results were presented to verify them.
2. Immobilization by single antigen-antibody reaction occurred according to schema (1). The reaction mechanism involving an intermediate complex was applicable to the antigen-antibody reaction in Paramecium.
3. Judging from this, it may be said that A and B antigens are quite different in molecular configurations.
4. The nature of immobilization was revealed by an analysis of the A+B∼a+b reaction. Thus it was concluded that schema (9) was valid, and the receptor for immobilization exhibited a somewhat amplifying mechanism.