Translocation and Trisomic Down's Syndrome in a Family with a Familial D/G Translocation

抄録

39 individuals in three generations of large kindred were studied by chromosomal analysis of cultured leukocytes. Of these 39, 11 are carriers of D/G translocation, two D/G translocation mongols and two mongols of the regular trisomic type. The translocation was carried through three generations which were studied. By some men an abnormally long Y chromosome was observed. The simultaneous occurrence of these chromosomal changes in one kindred is briefly discussed.