抄録
Chromosome studies of 112 patients with Down's syndrome are presented. Two (1.78%) had a sporadic D/G translocation, five (4.46%) had an inherited D/G translocation, one child (0.89%) exhibited a de novo G/G translocation. Two patients (1.78%) had a normal/trisomy G mosaicism, the remaining 102 patients (91.07%) had a regular trisomy 21. Seventy of 112 patients (62.50%) were born to mothers aged 30 years and younger. Other chromosomal aberrations (XYY syndrome, D/D translocation, abnormally long Y chromosome) were found in three families.
