Abstract
The AL/N mouse strain was found to have 38 chromosomes including two translocation submetacentrics identical to TlWh. Giemsa-banding showed that the TlWh AL/N translocation submetacentrics both involve chromosomes 5 and 19; meiotic studies of male (TlWh_??_×AL/N_??_) F1 hybrids confirmed these results. The origin and significance of TlWh and several other Robertsonian mouse translocations are discussed.