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Online ISSN : 2424-0664
Print ISSN : 0916-6920
ISSN-L : 2424-0664
原著
子宮体癌における細胞形態学的所見と相対的核DNA 量との関連性に関する基礎的検討
中井 英勝渡部 洋上田 晴彦星合 昊
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ジャーナル フリー

2006 年 16 巻 2 号 p. 19-23

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Relative DNA content of tumor cells determined by flowcytometric analysis (DNA ploidy) has been reported as a prognostic factor of solid cancer. However, it is still unknown correlation between morphologic characteristics and DNA ploidy. We have evaluated the cytopathologic findings including area of nucleus, area of nucleolus, number of nucleolus, nuclear/ cytoplasm ratio, and DNA ploidy in 76 patients with uterine endometrial carcinomas. DNA aneuploid was detected in 18 patients (24%), and DNA aneuploid cases exhibited significantly larger nuclear area and area of nucleolus than that of the DNA diploid cases. However, no correlation was seen in nuclear/cytoplasm ratio, and number of nucleolus. Our findings suggest that relative DNA content would be influenced to area of the nucleus and area of the nucleolus.

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