Drug Delivery System
Online ISSN : 1881-2732
Print ISSN : 0913-5006
ISSN-L : 0913-5006
Feature articles “Skin barrier function and recent trend in transdermal drug delivery systems” Editor : Kenji Sugibayashi
The present conditions and the prospects of a skin application drug
Tetsuya Watanabe
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JOURNAL FREE ACCESS

2007 Volume 22 Issue 4 Pages 450-457

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Abstract
Recently transdermal therapeutic systems(TTS) have been paid attention and thought to be greatly useful in patients due to advanced technology in enhancement of skin permeation and decreased side effect on the skin after the TTS was removed. Fentanyl TTS for the narcotic analgesics, tulobuterol tape for the asthma treatment and oxybutynin TTS for the urine incontinence treatment are of the examples. When the TTS products which are requested by the patients can be developed, they must be a target for the global development like oral formulations.
Here, I review the advantage and mechanism of the TTS products such as Durotep Patch, Hokunalin Tape, Oxytrol and Lidoderm in this report.
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© 2007 Japan Society of Drug Delivery System
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