Drug Delivery System
Online ISSN : 1881-2732
Print ISSN : 0913-5006
ISSN-L : 0913-5006
Feature articles “Development of new technologies toward the clinical trials of gene therapy” Editor : Mahito Nakanishi
Development of novel RNA vectors capable of stable and persistent gene expression
Mahito Nakanishi
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2007 Volume 22 Issue 6 Pages 620-627

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Abstract
Effective treatment of hereditary metabolic diseases requires long-term expression of therapeutic genes without chromosomal insertion. In this review, I describes the characteristics and application of unique RNA vectors capable of persistent gene expression with defect in interferon induction.
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© 2007 Japan Society of Drug Delivery System
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