Drug Delivery System
Online ISSN : 1881-2732
Print ISSN : 0913-5006
ISSN-L : 0913-5006
Feature articles “Development of new technologies toward the clinical trials of gene therapy” Editor : Mahito Nakanishi
Selective gene delivery into target cells by fiber-modified adenovirus
Kazunori KatoHirofumi Hamada
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2007 Volume 22 Issue 6 Pages 628-635

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Abstract
We focused on the function of fiber-modified adenovirus (Adv-FZ33) that contains a synthetic 33-amino acid derived from protein A. We established the comprehensive procedure for screening antibodies that increase transduction efficiency by binding Adv-FZ33 with various human cancers.
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© 2007 Japan Society of Drug Delivery System
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