Drug Delivery System
Online ISSN : 1881-2732
Print ISSN : 0913-5006
ISSN-L : 0913-5006
Feature articles “Vaccine in DDS” Editor : Shinsaku Nakagawa
Present and future of cancer vaccine
WT1 peptide-based cancer immunotherapy
Haruo Sugiyama
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Keywords: WT1, Wilms' tumor gene, immunotherapy, cancer
JOURNAL FREE ACCESS

2008 Volume 23 Issue 2 Pages 145-150

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Abstract
Wilms' tumor gene WT1 is overexpressed in leukemias and almost all types of solid tumors, and exerts an oncogenic function in leukemogenesis and tumorigenesis. WT1 protein is a pan-tumor associated antigen and we performed for the first time the WT1-peptide-based cancer immunotherapy and demonstrated its safety and clinical effect.
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© 2008 Japan Society of Drug Delivery System
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