Abstract
It is really expected to develop vaccines which are based on newly developed technologies, since we are facing to various emerging infectious diseases such as new influenza epidemic. Various vaccines for infants or children have been developed to use, but vaccines for adolescent such as human papilloma vaccine, and those for adults such as zoster vaccine have been recently developed in USA and Europe. Vaccines based on new concept such as recombinant vaccine, DNA vaccine, polypeptide vaccine and mucosal vaccine will be on market in near future. Furthermore, development of new adjuvants inducing high immunity but having few side-reaction is urgently needed.
