Drug Delivery System
Online ISSN : 1881-2732
Print ISSN : 0913-5006
ISSN-L : 0913-5006
Feature articles “Double targeted drug delivery : fusion of drug and medical device technologies” Editor : Teruo Okano
Development of polymeric micelles for innovative photodynamic therapy
Nobuhiro NishiyamaYuji MorimotoKazunori Kataoka
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2010 Volume 25 Issue 5 Pages 448-455

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Abstract
Photodynamic therapy (PDT) is an effective method for the treatment of superficial and early-stage cancers. The use of DDS for the delivery of photosensitizers is a promising approach for improved safety and enhanced efficacy of PDT. In this regard, we have developed polymeric micelles incorporating dendritic photosensitizers and demonstrated their usefulness in animal studies.
Also, we have established an innovative PDT system using the combination of polymeric micelles and light irradiation device for diagnosis and treatment of microcarcinoma.
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© 2010 Japan Society of Drug Delivery System
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