Drug Delivery System
Online ISSN : 1881-2732
Print ISSN : 0913-5006
ISSN-L : 0913-5006
Feature articles “Application of Drug Delivery Systems to Oligonucleotide Therapeutics” Editor : Yoshinobu Takakura
Drug discovery using a novel biomaterial of oligonucleotides and innovative DDS
Hiroaki Okada
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JOURNAL FREE ACCESS

2010 Volume 25 Issue 6 Pages 552-564

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Abstract

A novel biomaterial of therapeutic oligonucleotides such as siRNA and miRNA exactly brought a new paradigm shift in the drug discovery. The technologies to overcome the off-target effects, enzymatic and membrane barrier for attaining a new medicine of these oligonucleotides are overviewed.

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© 2010 Japan Society of Drug Delivery System
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