Drug Delivery System
Online ISSN : 1881-2732
Print ISSN : 0913-5006
ISSN-L : 0913-5006
[Feature articles] “Precise design and structural control of polymer materials for DDS” Editor:Atsushi Maruyama
Design of glyco polymer vesicles and their function as DDS nanofactories
Tomoki NishimuraKazunari Akiyoshi
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JOURNAL FREE ACCESS

2019 Volume 34 Issue 3 Pages 154-162

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Abstract
The development of drug delivery systems (DDS) that enable encapsulation of drugs, selective delivery to target tissues or organs, and release of drugs has improved therapeutic effect and reduced side effects. Although these conventional DDSs have valuable therapeutic effects, their effects are limited. Different approaches to the development of novel DDSs are hence desirable. Concepts such as DDS nanofactories are therefore attracting much attention. DDS nanofactories combine the features of nanoreactors and delivery carriers. They can produce drugs or transform toxic compounds into harmless compounds at disease sites. Here, we described the required features of DDS nanofactories and the characteristics of the molecular permeable glyco polymer vesicles and their functions as a DDS nanofactory.
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© 2019 The Japan Society of Drug Delivery System
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