Drug Delivery System
Online ISSN : 1881-2732
Print ISSN : 0913-5006
ISSN-L : 0913-5006
[Serial] Front line of DDS development in pharmaceutical industries
Formulation study and clinical development of transdermal drug delivery system for allergic rhinitis “ALLESAGA® TAPE”
Yasunari MichinakaSatoshi Amano
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JOURNAL FREE ACCESS

2019 Volume 34 Issue 3 Pages 208-212

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Abstract
ALLESAGA®TAPE is the first once-daily transdermal patch for treatment of allergic rhinitis in the world, which contains the second generation antihistamine drug, emedastine fumarate, as an active ingredient. As a result of the phase III comparative study for patients with seasonal allergic rhinitis, the emedastine patches 4mg and 8mg showed superiority to the placebo. The efficacy of the emedastine patch has been also confirmed in all time zones including nighttime to early morning likely by stable blood emedastine concentration. This article describes the formulation and clinical characteristics of ALLESAGA®TAPE.
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© 2019 The Japan Society of Drug Delivery System
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