Drug Delivery System
Online ISSN : 1881-2732
Print ISSN : 0913-5006
ISSN-L : 0913-5006
[Feature articles] “Pioneer technologies of the extracelluar vesicle-based drug discovery and diagnosis” Editor:Hidetaka Akita
Extracellular vesicle hybrid engineering for DDS and medical application
Ryosuke MizutaKazunari Akiyoshi
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JOURNAL FREE ACCESS

2021 Volume 36 Issue 2 Pages 90-99

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Abstract

Extracellular vesicles (EVs) have attracted much attention as new therapeutic agents and DDS carriers. In recent years, there has been a great deal of progress in the development of technologies for modifying EVs to acquire new functions. In this paper, we summarize the current challenges for DDS applications of EVs and introduce recent research on the functionalization of EVs. In particular, we review the research on extracellular vesicle hybrid engineering, which aims to impart functions by conjugation and complexation of various functional molecules, nanocarriers, and inorganic nanoparticles with EVs.

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© 2021 The Japan Society of Drug Delivery System
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