2021 Volume 36 Issue 2 Pages 90-99
Extracellular vesicles (EVs) have attracted much attention as new therapeutic agents and DDS carriers. In recent years, there has been a great deal of progress in the development of technologies for modifying EVs to acquire new functions. In this paper, we summarize the current challenges for DDS applications of EVs and introduce recent research on the functionalization of EVs. In particular, we review the research on extracellular vesicle hybrid engineering, which aims to impart functions by conjugation and complexation of various functional molecules, nanocarriers, and inorganic nanoparticles with EVs.