Abstract
Living cells are expected to be one of the functional active pharmaceutical ingredients, and the development of in vitro cell manipulation techniques are desired. Cells express their functions not only on the surface of the substrate but also in contact with biointerfaces of various dimensions such as molecular assemblies （nanogel aggregates） and hydrogel environments （three-dimensional environments） in vitro. Therefore, in order to develop new cell manipulation techniques, it is essential to prepare platform interfaces using biomaterials as elements focusing on biocompatibility and cell affinity. In this article, it is proposed that introduce a biointerface technology that extends cell affinity to various dimensions by molecular design of phospholipid polymers 2-methacryloyloxyethyl phosphorylcholine （MPC） polymers.
