Abstract
With the worldwide use of mRNA-lipid nanoparticle, one concern regarding the most commonly used material, polyethylene glycol (PEG), in the field of drug delivery has made a small wave. Although this wave is not directly related to the main purpose of improving efficacy of therapeutics in DDS society, however, I think, it is necessary for DDS society to understand the current situation. This roundtable discussion will be an opportunity for industry and academia to discuss not only the perspective of DDS material, but also the perspectives of pharmaceutical filed and biomaterial filed and to declare what we should do in the future based on knowledge from the past to the present, and we hope to make a big wave from Japan.