Abstract
The effect of lysophosphatidylcholine (LPC) on intestinal absorption of carboxyfluorescein was studied in rat small and large intestines. We found that LPC markedly enhanced the absorption of CF in the large intestine as well as the small intestine in concentration-dependent manner, The minimum effective concentrations in the large intestine and the small intestine were 0.25% and 1.0% respectively, These results showed that LPC acted as strong absorption enhancer and was more effective on the large intestine than on the small intestine similarily to the other absorption enhancers.
