Drug Discoveries & Therapeutics
Reviews
Nitric oxide donor hybrid compounds as promising anticancer agents
Qin-ge Ding,Jie ZangShuai GaoQianwen GaoWenwen DuanXiaoyang LiWenfang XuYingjie Zhang
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Volume 10 (2016) Issue 6 Pages 276-284

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Abstract

Nitric oxide (NO) plays important roles in cardiovascular regulation, nerve transmission delivery and immune responses. In the last semicenturry, it has been proved that though low concentration of NO is tumor-promoting, high concentration of NO could exhibit multiple antitumor effects, which led to the research and development of kinds of NO donors and NO donor hybrid compounds as antitumor agents. Herein, the recent development of NO donor hybrid compounds is briefly reviewed.

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© 2016 International Research and Cooperation Association for Bio & Socio-Sciences Advancement
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