Drug Discoveries & Therapeutics
Online ISSN : 1881-784X
Print ISSN : 1881-7831
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The exercise paradox may be solved by measuring the overall thrombotic state using native blood
Hideo IkarugiJunichiro Yamamoto
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Volume 11 (2017) Issue 1 Pages 15-19

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Abstract

While exercise is widely believed to prevent atherothrombotic diseases, it occasionally causes sudden death. This exercise paradox may be due to the inadequate testing of the thrombotic and thrombolytic status. A recently developed shear-induced thrombosis/endogenous fibrinolysis test performed with non-anticoagulated blood samples allows the assessment of the thrombotic state of an individual both at rest and after exercise. This sensitive and physiologically relevant test may help to solve the aforementioned exercise paradox.

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© 2017 International Research and Cooperation Association for Bio & Socio-Sciences Advancement
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