Drug Discoveries & Therapeutics
Online ISSN : 1881-784X
Print ISSN : 1881-7831
ISSN-L : 1881-7831
Original Articles
Suppressive effects of whey protein hydrolysate on sucrose-induced hyperglycemia in silkworms
Yasuhiko MatsumotoMiki TakahashiMasahiro UmeharaMasato AsanoHiroko Maruki-UchidaMinoru MoritaKazuhisa Sekimizu
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2019 Volume 13 Issue 5 Pages 244-247

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Abstract

Silkworms are useful for evaluating substances that suppress postprandial hyperglycemia by oral administration. In this study, orally administered whey protein hydrolysate (WPH), obtained by enzymatic treatment of whey protein, suppressed sucrose-induced hyperglycemia in silkworms in a dose-dependent manner. WPH also inhibited glucose-induced hyperglycemia in silkworms. These findings suggest that WPH contains a bioactive peptide that inhibits glucose uptake from the intestinal tract and thereby suppresses sucrose-induced hyperglycemia.

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© 2019 International Research and Cooperation Association for Bio & Socio-Sciences Advancement
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