Drug Discoveries & Therapeutics
Online ISSN : 1881-784X
Print ISSN : 1881-7831
ISSN-L : 1881-7831
Commentary
Treat 2019 novel coronavirus (COVID-19) with IL-6 inhibitor: Are we already that far?
Yuanyuan ZhangYanyan ZhongLin PanJing Dong
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JOURNALS FREE ACCESS

2020 Volume 14 Issue 2 Pages 100-102

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Abstract

The world is in the midst of the coronavirus disease 2019 (COVID-19) pandemic. Interleukin 6 (IL-6) inhibitor (tocilizumab) had been suggested for the treatment of acute respiratory distress syndrome (ARDS) patients based on the concept of "cytokine storm" in COVID-19. However, we still lack reliable studies to verify "cytokine storm" in COVID-19 pneumonia. Furthermore, IL-6 inhibitor has potential hazards of inducing infectious diseases. The efficacy of IL-6 monoclonal antibody-directed therapy remains to be fully evaluated.

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© 2020 International Research and Cooperation Association for Bio & Socio-Sciences Advancement
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