Drug Discoveries & Therapeutics
Online ISSN : 1881-784X
Print ISSN : 1881-7831
ISSN-L : 1881-7831
Brief Report
Positron-emission-tomography in tubercular lymphadenopathy: A study on its role in evaluating post-treatment response
Abhishek SinghMadhavi TripathiParul KodanNitin GuptaNeeraj NischalPankaj JorwalArvind KumarAnimesh RayManish SonejaNaveet Wig
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2021 Volume 15 Issue 1 Pages 35-38

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Abstract

Lymph node tuberculosis is one of the most common forms of extrapulmonary tuberculosis worldwide. The study aimed to evaluate the role of positron emission tomography-computed tomography (PET-CT) in determining post-treatment response in lymph node tuberculosis. A PET-CT was done in all treatment naïve tubercular lymphadenitis adults at baseline and after six months of therapy. The post-treatment clinical response was compared with the metabolic response on PET-CT. Of the 25 patients with tubercular lymphadenitis, 9/25 patients showed a complete metabolic response (CMR) at six months, while 16 patients had a partial metabolic response (PMR). All patients with CMR had a good clinical response. However, discordance between clinical and PET findings was noticed in those with PMR. The role of PET-CT in evaluating post-treatment response in patients with tubercular lymphadenitis needs further evaluation with a larger sample size.

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© 2021 International Research and Cooperation Association for Bio & Socio-Sciences Advancement
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