Drug Discoveries & Therapeutics
Online ISSN : 1881-784X
Print ISSN : 1881-7831
ISSN-L : 1881-7831
Brief Report
A new boronic acid-based fluorescent sensor for L-dihydroxy-phenylalanine
Zhongyu WuXinying YangWenfang XuBinghe WangHao Fang
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2012 Volume 6 Issue 5 Pages 238-241

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Abstract

Catecholamines, such as dopamine and L-dihydroxyphenylalanine (L-DOPA), are associated with different physiological functions and diseases. In our recent studies, a novel water-soluble boronic acid compound 3c was identified as a selective fluorescent sensor for L-DOPA. This compound not only has the ability to interact with dopamine and catechol, but also has no fluorescence intensity change for L-DOPA precursors in vivo, such as L-tyrosine.

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© 2012 International Research and Cooperation Association for Bio & Socio-Sciences Advancement
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