Drug Discoveries & Therapeutics
Online ISSN : 1881-784X
Print ISSN : 1881-7831
ISSN-L : 1881-7831
The role of growth factors in nerve regeneration
Mehmet Emin ÖngerBurcu DelibaşAysın Pınar TürkmenErkan ErenerBerrin Zuhal AltunkaynakSüleyman Kaplan
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JOURNAL FREE ACCESS Advance online publication

Article ID: 2016.01058


Nerve injuries result in functional loss in the innervated organ or body parts, and recovery is difficult unless surgical treatment has been done. Different surgical treatments have been suggested for nerve repair. Tissue engineering related to growth factors has arisen as an alternative approach for triggering and improving nerve regeneration. Therefore, the aim of this review is to provide a comprehensive analysis related to growth factors as tools for optimizing the regeneration process. Studies and reviews on the use of growth factors for nerve regeneration were compiled over the course of the review. According to literature review, it may be concluded that growth factors from different sources present promising treatment related to nerve regeneration involved in neuronal differentiation, greater myelination and axonal growth and proliferation of specific cells for nerve repair.

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© 2016 International Research and Cooperation Association for Bio & Socio-Sciences Advancement