Nitric oxide donor hybrid compounds as promising anticancer agents

Qin-ge Ding,; Jie Zang; Shuai Gao; Qianwen Gao; Wenwen Duan; Xiaoyang Li; Wenfang Xu; Yingjie Zhang

doi:10.5582/ddt.2016.01067

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Nitric oxide donor hybrid compounds as promising anticancer agents

Qin-ge Ding,, Jie Zang, Shuai Gao, Qianwen Gao, Wenwen Duan, Xiaoyang Li, Wenfang Xu, Yingjie Zhang

著者情報

キーワード: NO releasing agents, antitumor, NOSs, furoxan, NO-NSAIDs

ジャーナルフリー早期公開

論文ID: 2016.01067

DOI https://doi.org/10.5582/ddt.2016.01067

この記事には本公開記事があります。

The final version of this article is now available: Vol. 10 (2016), No. 6 pp. 276-284

詳細

抄録

Nitric oxide (NO) plays important roles in cardiovascular regulation, nerve transmission delivery and immune responses. In the last semicenturry, it has been proved that though low concentration of NO is tumor-promoting, high concentration of NO could exhibit multiple antitumor effects, which led to the research and development of kinds of NO donors and NO donor hybrid compounds as antitumor agents. Herein, the recent development of NO donor hybrid compounds is briefly reviewed.

責任著者(Corresponding author)

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