A Case of Desmoplastic Malignant Melanoma

Abstract

A 68-year-old male patient had a black macular lesion with a subcutaneous nodule on his left cheek. Histopathological findings of the superficial lesion included proliferation of atypical melanocytes in solitary units or small nests. The findings of the subcutaneous nodule showed marked proliferations of fibrous tissue containing atypical spindle tumor cells without melanin pigments. Immunopathologically, the spindle tumor cells were positive for vimentin and S-100 protein but negative for HMB-45. The diagnosis of desmoplastic malignant melanoma was established.