The Japanese Journal of Dermatology
Online ISSN : 1346-8146
Print ISSN : 0021-499X
ISSN-L : 0021-499X
Original Articles
On the Validity of Skin Biopsies of Normal-Looking Axilla in Patients with Genital Extramammary Paget’s Disease
Toshihiro TakaiYozo Murata
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2013 Volume 123 Issue 12 Pages 2257-2261

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Abstract
We report the results of skin biopsies of normal-looking axilla in 30 patients with genital extramammary Paget’s disease. Among all of the cases, only one exhibited intraepidermal clear cells at one side of the axilla. In this case, the clear cells had only a sparse and limited distribution, as in most of other previous case reports dealing with axillary occult Paget’s disease. We suggest that so-called occult Paget’s disease may include Toker cells or clinically overlooked Paget’s disease with subtle skin changes. We conclude that careful inspection is crucial rather than unnecessary random axillary skin biopsies.
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© 2013 Japanese Dermatological Association
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