2020 Volume 130 Issue 12 Pages 2557-2565
A continuous glucose monitoring system, FreeStyle Libre, that measures interstitial glucose level, has been introduced in Japan since 2017. Two cases of allergic contact dermatitis related to the sensor devise has been reported to date. Here we report three cases that developed erythema where the sensor was applied. Three patients exhibited erythema when a patch test was performed with the adhesive part of the sensor, and were diagnosed with allergic contact dermatitis. Two out of three were further tested with the components of adhesive tape, and isobornyl acrylate was identified as a culprit allergen. Out of 15 diabetic patients who used FreeStyle Libre in our hospital, three patients were diagnosed by patch test and two additional patients also had erythema and pruritus, although the latter were not diagnosed by the patch test. Due to the increasing use of the devise, the allergen should be considered in future diagnosis.
