Evaluation of Autonomously Functioning Thyroid Nodule by 3-dimensional^99mTc-pertechnetate Thyroid SPECT/CT Imaging

Abstract

Two-dimensional ^99mTcO₄^- scintigraphy using a gamma camera is widely used as a simple test method that can simultaneously evaluate the morphology and function of the thyroid gland. However, some thyroid diseases require three-dimensional (3D-) morphological evaluation and evaluation of local accumulation. In this study, we used SPECT/CT to verify the quantitative evaluation of autonomously functioning thyroid nodule (AFTN) cases and the measurement of ^99mTcO₄^- uptake rate. In the diagnosis of AFTN, 3D-morphological and functional information was obtained by using ^99mTcO₄^- SPECT/CT. Furthermore, it was clarified that the intake rate obtained by ^99mTcO₄^- SPECT/CT had the same quantitativeness as the conventional method.